Sir Julian Lewis: The hon. Lady mentioned the all-important fact that early diagnosis, coupled with the prescribing of a quite common antibiotic – I believe amoxicillin is one of them – can make a crucial difference. In May last year, I asked in a written question whether the Secretary of State for Health and Social Care would take steps to facilitate the circulation of material to general practitioners, advising them on how to recognise PANS and PANDAS, and treat them with antibiotics and anti-inflammatory medications. The response that I got from the Minister for Care was that this is all a matter for the National Institute for Health and Care Excellence, which is an independent body. The Minister said that NICE has

“no plans to issue guidance on paediatric acute-onset neuropsychiatric syndrome (PANS) and paediatric autoimmune neuropsychiatric disorder associated with streptococcus (PANDAS)”.

He also said,

“should the evidence base develop further, we would look to the NICE to update clinical policy.”

It seems that the early use of antibiotics is not yet accepted by the medical establishment. Does the hon. Lady know whether there is hard evidence to show that the medical establishment needs to get its act together on the matter?

Wendy Chamberlain: The right hon. Member may recall the debate we had in a previous Parliament on this subject. The Minister at the time gave the commitment that she would ensure that GPs and other medical practitioners were aware of the guidance that PANS PANDAS UK was producing. I hope we will hear today that the Minister is looking at that. There is clearly a challenge, and although the condition is recognised by the World Health Organisation and by NHS England, there is more to do to minimise the postcode lottery and ensure that we can get support for young people.

Sir Julian Lewis: I am sorry if I did not express myself clearly enough. It is not so much a question of the non-recognition of PANS and PANDAS, but whether it has been recognised that early treatment with antibiotics can make all the difference.

Wendy Chamberlain: I am sure the Minister can address that in her closing remarks. We absolutely need to ensure that. As the right hon. Member has said, amoxicillin might be one of the antibiotics that could be used. It is straightforward to use, and in the vast majority of cases it works, but if it does not, potentially PANS and PANDAS could be ruled out. …

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Sir Julian Lewis: At the risk of labouring the same single point I want to make again and again, there really does seem to be no downside to telling all GPs that if there is any question at all that a child might have PANS or PANDAS, the GP should prescribe them one of the basic antibiotics, because they could benefit from it tremendously, and there is no risk of harm.

Freddie van Mierlo: I wholeheartedly agree with the right hon. Gentleman. There are very few downsides of prescribing an antibiotic, especially in this instance, given the seriousness of the condition. As he says, there is really no good reason to withhold this medication. …

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Sir Julian Lewis: I detected that the Minister was moving towards her conclusion, so I thought I would intervene before she did. She has a fine record, before she became a Minister, of campaigning on mesh-damaged women. That was an occasion where something simple was done that led to very complicated problems. Here, we have a complicated condition, but it is thought that something simple could be done – namely, guidance should be given to all GPs that if this condition is even suspected, a simple course of antibiotics should be given. I have not yet heard anything in what she has said as to whether the research backs that up. If the research has not been done, will she undertake to make sure it gets done and that general practitioners are advised accordingly?

The Parliamentary Under-Secretary of State for Health and Social Care (Mrs Sharon Hodgson): I thank the right hon. Gentleman, who I have worked closely with on a number of health matters over a number of years, and he mentions the work that we did together on mesh. I studied my speech after listening to your earlier intervention and the conversation about antibiotics –

Madam Deputy Speaker (Ms Nusrat Ghani): Order. It was not my intervention, but that of the right hon. Member for New Forest East (Sir Julian Lewis).

Mrs Hodgson: Thank you, Madam Deputy Speaker. I should know better after 21 years in this House; it just goes to show – you can always teach an old dog new tricks.

Following the right hon. Gentleman’s intervention on antibiotics, I noticed that there was nothing about that in my speech, so I have come to the conclusion that that will come forward in the guidance later this year. I will be looking for that closely, and I am sure that my officials heard the point mentioned in the debate. As the right hon. Gentleman says, if a simple course of antibiotics is going to make all the difference, we would want to ensure that it is provided.

In closing, I want to emphasise that the experiences of children and families affected by PANS/PANDAS are real and significant, and that we are taking action to strengthen the system and deliver meaningful change. Our responsibility is to respond with compassion, to listen carefully, and to ensure that support is accessible, timely and appropriate. By strengthening clinical awareness, improving integration across services and continuing to build the evidence base, we can move towards a system that delivers better recognition, more effective support, and improved outcomes for children and young people, and their families.